Here is a tough call:
Give up all hopes of acknowledgment of your good deeds, your affections, your aspirations, your opinions, and ultimately your love.
Give up all expectations.
And now, assuming that you are surrounded by such an extremely indifferent universal vacuum, proceed to live your live filled with the fierce joy of knowing that you can still do all these things, still burn with the fire of the self, and that the reactions of others -- or lack of such -- matter less than the light breath of wind upon a great flaming furnace.
Remain aflame, because you must.
And because the above scenario is false.